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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Lactococcus lactis provides an efficient platform for production of disulfide-rich recombinant proteins from Plasmodium falciparum

Fig. 4

Antigenic analysis of different target recombinant proteins expressed and purified from L. lactis culture. Total IgG prevalence as observed in 54 malaria hyperimmune Liberian sera against purified recombinant proteins as determined through multiplex analysis. a Antigenic analysis of recombinant proteins derived from membrane anchored P. falciparum antigens which include the GPI-anchored and transmembrane domain containing antigens from secretory organelles (micronemes and rhoptries). b Antigenic analysis of recombinant proteins derived from P. falciparum antigens which are peripherally associated with merozoite surface. The horizontal lines mark the cutoff-levels determined by the mean fluorescence intensity (MFI) +2 standard deviations of reactivity of sera from Danish donors who have never been exposed to malaria infection. The numbers listed above scatter plot for each antigen represent the percentage of hyperimmune sera which show positive reactivity against the respective antigen

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