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Table 4 Influence of PitA deficiency and enhancement on His production

From: Specific features of l-histidine production by Escherichia coli concerned with feedback control of AICAR formation and inorganic phosphate/metal transport

Strain

OD540

His, g/L

His accumulation, %

KF37

14.9 ± 0.3

3.4 ± 0.1

100

KF37 [ΔpitA::KmR]

11.3 ± 0.5

3.8 ± 0.3

112

KF37 [CmR-PLtac-pitA]

7.1 ± 0.2

1.4 ± 0.2

41

  1. Average data from 6 independent experiments are represented
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Microbial Cell Factories

ISSN: 1475-2859

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