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Table 4 Influence of PitA deficiency and enhancement on His production

From: Specific features of l-histidine production by Escherichia coli concerned with feedback control of AICAR formation and inorganic phosphate/metal transport

Strain OD540 His, g/L His accumulation, %
KF37 14.9 ± 0.3 3.4 ± 0.1 100
KF37 [ΔpitA::KmR] 11.3 ± 0.5 3.8 ± 0.3 112
KF37 [CmR-PLtac-pitA] 7.1 ± 0.2 1.4 ± 0.2 41
  1. Average data from 6 independent experiments are represented