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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Specific features of l-histidine production by Escherichia coli concerned with feedback control of AICAR formation and inorganic phosphate/metal transport

Fig. 4

Schematic view of the putative role of PitA deficiency in the cellular Pi/PPi balance and histidine biosynthetic pathway. ATP adenosine triphosphate, PP i inorganic pyrophosphate, P i inorganic orthophosphate, Me2+-P i metal phosphate complexes, PRPP phosphoribosyl pyrophosphate, PR-ATP phosphoribosyl-ATP, PR-AMP phosphoribosyl-adenosine monophosphate, ADP adenosine diphosphate, L-His l-histidine, HisGE271K feedback-resistant ATP-phosphoribosyltransferase, HisI phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase, Ppa inorganic pyrophosphatase, PitA low affinity Pi transport system, PstSCAB phosphate specific transport system

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