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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Metabolic engineering of the 2-ketobutyrate biosynthetic pathway for 1-propanol production in Saccharomyces cerevisiae

Fig. 1

Pathways for 1-propanol production in S. cerevisiae. a–d show different theoretical methods to achieve production of this metabolite. Red letters indicate genes that are overexpressed. Blue and green letters indicate genes that are deleted. ARO3 and ARO4 encode 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase. ALT1 and ALT2 encode alanine transaminase. CIT1, CIT2 and CIT3 encode citrate synthase. MET2 encodes l-homoserine-O-acetyltransferase. GLY1 encodes threonine aldolase. ILV2 and ILV6 encode acetolactate synthase. ILV3 encodes dihydroxyacid dehydratase. ILV5 encodes acetohydroxyacid reductoisomerase. BAT1 and BAT2 encode branched-chain amino acid transaminase. cimA encodes citramalate synthase. leuC and leuD encode citramalate hydrolyase. LEU2 encodes 3-isopropylmalate dehydrogenase. asd encodes aspartate-semialdehyde dehydrogenase. thrA encodes aspartokinase and homoserine dehydrogenase I. thrB encodes homoserine kinase. thrC encodes threonine synthase. tdcB encodes threonine dehydratase

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Microbial Cell Factories

ISSN: 1475-2859

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