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Fig. 8 | Microbial Cell Factories

Fig. 8

From: Expression of a recombinant hybrid antimicrobial peptide magainin II-cecropin B in the mycelium of the medicinal fungus Cordyceps militaris and its validation in mice

Fig. 8

Antibacterial and immunomodulatory functions of the C. militaris producing Mag II-CB and CB in mice. The numbers of E. coli, Lactobacillus and Bifidobacterium in the cecum (a) were counted. The Ileum mRNA levels of ZO-1 (b), claudin-1 (c) and occludin (d) were analyzed by real-time RT-PCR. Plasma IgA (e), IgM (f), IgG (g) and ileum sIgA (h) levels were measured using ELISA kits. The ileum-specific inflammatory cytokine levels for IL-6 (i), TNF-α (j) and IL-10 (k) were also measured by real-time RT-PCR. The final values were the mean ± SE, and values without the same letters are significantly different (P < 0.05)

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Microbial Cell Factories

ISSN: 1475-2859

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