Fig. 3
From: Engineering E. coli for simultaneous glucose–xylose utilization during methyl ketone production
Overview of central carbon metabolism in E. coli highlighting strategies (in red) to improve NADPH supply in the sugar co-utilizing strain XW1014. G6P, glucose 6-phosphate; F6P, fructose 6-phosphate; FBP, fructose 1,6-bisphosphate; DHAP, dihydroxyacetone phosphate; GAP, glyceraldehyde 3-phosphate; 13BPG, 1,3-bisphosphoglycerate; 3PG, 3-phosphoglycerate; 2PG, 2-phosphoglycerate; PEP, phosphoenolpyruvate; Pyr, pyruvate; AcCoA, acetyl-CoA; 2KG: 2-ketoglutaric acid; 6PGL, 6-phosphogluconolactone; 6PG, 6-phosphogluconate; Ru5P, ribulose 5-phosphate; R5P, ribose 5-phosphate; X5P, xylulose 5-phosphate; S7P, sedoheptulose 7-phosphate; E4P, erythrose 4-phosphate; pgi, glucose 6-phosphate isomerase; maeB, malic enzyme; zwf, glucose 6-phosphate dehydrogenase; gnd, phosphogluconate dehydrogenase