Table 1 Comparison of yield and methodologies employed in the native producers of coenzyme Q10

Schizosaccharomyces pombe

1.35

[83, 162]

Overexpression of native HMGR gene

Sporidiobolus johnsonii

10

[78]

Addition of exogenous HBA

Rhodobacter sphaeroides

12.96

[87]

Overexpression of multiple MEP pathway genes coupled with fine-tune of quinone modification pathway genes

Agrobacterium tumefaciens

6.92

[83, 163]

Ectopic expression of DXS and DPS genes in optimized media