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Table 1 Comparison of yield and methodologies employed in the native producers of coenzyme Q10

From: Cellular factories for coenzyme Q10 production

Native hosts for coenzyme Q10 production
Host Yield (mg/g DCW) Ref Methodologies
Schizosaccharomyces pombe 1.35 [83, 162] Overexpression of native HMGR gene
Sporidiobolus johnsonii 10 [78] Addition of exogenous HBA
Rhodobacter sphaeroides 12.96 [87] Overexpression of multiple MEP pathway genes coupled with fine-tune of quinone modification pathway genes
Agrobacterium tumefaciens 6.92 [83, 163] Ectopic expression of DXS and DPS genes in optimized media