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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Elucidation of the glycosylation steps during biosynthesis of antitumor macrolides PM100117 and PM100118 and engineering for novel derivatives

Fig. 4

Production of PM100117 (1) and PM100118 (2) biosynthesis intermediates 10–13 in glycosyltransferase gene mutant strains. UPLC analysis at 254 (a) and 216 nm (b) wavelength of metabolite production in S. caniferus GUA-06-05-006A wild-type and ΔgonG1, ΔgonG2, ΔgonG3and ΔgonG4 deletion mutants. NR: peak non-related to PM100117/18. c Chemical structure of various PM100117/18 analogues

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Microbial Cell Factories

ISSN: 1475-2859

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