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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570

Fig. 4

Individual overexpression of artB, artX as well as artB & artX in S. aurantiacus remarkably enhances ATM-A production. a HPLC analysis of the ATM-A production by relevant S. aurantiacus recombinants. b Comparative analysis of the ATM-A production by target strains. WT, S. aurantiacus wild type; WT::pIB139, S. aurantiacus containing pIB139 as negative control; WT::artX, S. aurantiacus containing pIB139/artX; WT::artB, S. aurantiacus containing pIB139/artB; WT::artB & artX, S. aurantiacus containing pIB139/artB & artX. All measurements were conducted in triplicate

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