Fig. 8
From: Rewiring a secondary metabolite pathway towards itaconic acid production in Aspergillus niger
Controlled batch cultivations of citB overexpressing mutants. HPLC analysis of controlled batch cultivations of CitB #77 and #101. a Production of IA starts simultaneously for both strains after 36Â h where CitB#77 ends with a final titer of 16.98Â g/L IA after 192Â h and CitB #101 reaches a final titer of 9.82Â g/L. These two strains also produce CA, unlike the CitB #99 and #113 strains. CitB #77 produces a final titer of 1.9Â g/L CA and CitB #101 produces 3.9Â g/L CA. b Biomass development during controlled batch cultivations of CitB #77 and #101