Fig. 3
From: Rewiring a secondary metabolite pathway towards itaconic acid production in Aspergillus niger
Controlled batch cultivation of itaconic acid producing A. niger transformants. Controlled batch cultivation of AB1.13 strains carrying the full IA biosynthesis cluster. a HPLC analysis of organic acid production during controlled batch cultivations of AB1.13 strains #08, #49 and #63. The highest IA titer is achieved by AB1.13 #49 (11.74Â g/L). AB1.13 #08 produces the most CA (21.99Â g/L) from all three strains and achieves the lowest IA titer (2.48Â g/L). AB1.13 #63 produces 9.52Â g/L IA and 18.03Â g/L CA. b Biomass development and glucose consumption during controlled batch cultivations of strains #08, #49 and #63