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Table 3 Occurrence of false-positive clones when using pAHBgl-GFP compared to pAHBgl-GFP-CYC

From: Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector optimization

Vector

Total clones

False-positive clones (no./ %)

Χ2 value

p value

pAHBgl-GFP

845

64/8

–

–

pAHBgl-GFP-CYC

120

0/0

10.91

0.0001–0.001

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Microbial Cell Factories

ISSN: 1475-2859

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