From: Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector optimization
Group
No. of clones
Characteristics
High producers
29
High GCN and high expression
Overachievers
21
Low GCN and high expression
Underachievers
40
High GCN and low expression
Low-/non-producers
100
Low/no GCN and expression