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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Yeast-based assays for screening 11β-HSD1 inhibitors

Fig. 3

Effect of carbenoxolone (CBX) on 11β-HSD1 dependent response in the strains RVY97. 11β-HSD1 dependent yEGFP fluorescence of strain RVY97 treated with 250 μM cortisone and increasing CBX concentrations. Increasing concentration of carbenoxolone (up to 3 μM) led to a decreasing green fluorescence in the yeast population indicating a progressive inhibition of 11β-HSD1. The fluorescence of untreated cells (no CBX) was set at 1. Data shown represent means ± standard deviations of three independent experiments

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Microbial Cell Factories

ISSN: 1475-2859

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