Table 1 Deduced functions of ORFs in PM100117 and PM100118 biosynthetic gene cluster

orf1

264

WP_030324639.1

84/92

Aspartate dehydrogenase

orf2

265

WP_030324637.1

77/83

Hydrolase

orf3

173

WP_018535062.1

94/98

Cupin domain-containing protein

orf4

228

EDY62802.1

81/86

3-Ketoacyl-(acyl-carrier-protein) reductase

orf5

260

WP_005320771.1

83/89

Short-chain dehydrogenase

orf6

541

WP_033304767.1

82/87

Acetolactate synthase

orf7

313

WP_005320767.1

79/85

Ferredoxin

orf8

75

WP_031101148.1

70/75

Hypothetical protein

orf9

337

WP_033304770.1

88/93

3-Phenylpropionate dioxygenase

gonMR

176

WP_030624728.1

92/95

MarR family transcriptional regulator

gonL1

959

WP_006607813.1

86/90

LuxR family transcriptional regulator

gonL2

241

EJJ02892.1

80/84

LuxR family transcriptional regulator

gonL3

939

WP_006607811.1

80/87

LuxR family transcriptional regulator

gonD1

469

WP_006607808.1

90/94

NDP-hexose 2,3-dehydratase

gonP1

4219

AJE81080.1

60/69

Type I polyketide synthase

(loading module and modules 1 and 2)

gonP2

4939

AAZ94388.1

57/68

Type I polyketide synthase

(modules 3 to 5)

gonP3

3959

EJJ02484.1

86/89

Type I polyketide synthase

(modules 6 and 7)

gonP4

5234

EJJ02491.1

86/90

Type I polyketide synthase

(modules 8 to 10)

gonP5

8461

EDX25447.1

55/67

Type I polyketide synthase

(modules 11 to 15)

gonP6

5238

EJJ02498.1

87/90

Type I polyketide synthase

(modules 16 to 18)

gonP7

3641

EJJ02497.1

87/91

Type I polyketide synthase

(modules 19 and 20)

gonF1

67

WP_006608219.1

76/80

Ferredoxin

gonG1

415

ABO28820.1

66/80

Glycosyltransferase

gonGS

358

WP_006608216.1

94/97

Glucose-1-phosphate thymidylyltransferase (glucose synthase)

gonD2

333

WP_040902050.1

91/93

dTDP-glucose 4,6-dehydratase

gonR1

356

WP_051007140.1

70/79

NDP-4-keto-6-deoxyhexose reductase

gonG2

408

WP_006608213.1

74/83

Glycosyltransferase

gonD3

433

BAP34744.1

73/84

NDP-hexose-3,4-dehydratase

gonSL

1107

WP_006608212.1

68/78

AMP-dependent synthetase and ligase (acyl-CoA ligase, DH, KR, ACP)

gonS1

347

WP_040902110

82/91

3-oxoacyl-ACP synthase III

gonA

146

WP_040902049

72/84

Cold-Shock DNA-binding domain-containing protein

gonG3

402

WP_006608209

55/68

Glycosyltransferase

gonMT

345

WP_014208548

49/62

Methylase involved in ubiquinone/menaquinone biosynthesis

gonS2

344

WP_040246457

81/90

3-Oxoacyl-ACP synthase III

gonP8

2408

WP_006608212

58/59

Type I polyketide synthase

(loading module and extension module 1)

gonG4

368

WP_042158955

89/93

Glycosyltransferase

gonT1

286

WP_040902100.1

83/92

Multidrug ABC transporter permease

gonT2

260

WP_006608193.1

89/94

Multidrug ABC transporter permease

gonR2

319

AAB63047.1

49/63

dTDP-4-keto-2,3,6-trideoxyhexulose reductase

gonE

211

WP_006608191.1

83/89

dTDP-4-deoxyglucose 3,5-epimerase

gonCM

410

AKT74284.1

79/87

NDP-hexose-3-C-methyltransferase

gonH1

252

WP_006608189.1

79/88

Hypothetical protein

gonT

256

WP_006608180.1

90/94

Thioesterase

gonM1

301

WP_046708157.1

77/86

Menaquinone biosynthesis protein (chorismate dehydratase)

gonM2

407

EJJ02566.1

96/97

Menaquinone biosynthesis protein (dehypoxanthine futalosine cyclase)

gonF2

101

WP_006608177.1

94/96

Ferredoxin

gonM3

387

WP_006608176.1

98/99

Menaquinone biosynthesis protein (aminofutalosine synthase)

gonM4

291

WP_006608174.1

87/91

Menaquinone biosynthesis protein (1,4-dihydroxy-6-naphthoate synthase)

gonR3

364

WP_006608173.1

91/94

NDP-hexose 3-ketoreductase

gonCP

482

WP_006608172.1

91/95

Cytochrome P450

orf10

264

WP_030985702.1

88/92

3-Oxoacyl-ACP reductase

orf11

128

WP_053688399.1

86/91

HxlR family transcriptional regulator

orf12

174

WP_051733431.1

93/96

Hypothetical membrane protein

orf13

355

WP_037651728.1

90/93

NADPH: quinone reductase