Fig. 6
From: Key role of lipid management in nitrogen and aroma metabolism in an evolved wine yeast strain
Modification of gene expression before (35 g/l of CO2 released) and after (70 g/l of CO2 released) the change in bioconversion yield between higher alcohols and acetate esters for the evolved strain. a Multivariate factorial analysis (MFA) of the genes obtained by sparse PLS-DA and 13 metabolites or ratios. Each fermentation is identified by the labels X and Y, where X corresponds to the strain and Y is the timing of sampling. 1: Genes involved in sterol biosynthesis and oxido-reduction process; 2: Genes involved in translation; 3: Genes involved in cellular amino acid biosynthetic process, 4: Genes involved in DNA repair. ISA.ISO ratio of isobutyl acetate to isobutanol, IAA.IA ratio of isoamyl acetate to isoamyl alcohol. b Comparison of expression of genes involved in the sterol biosynthesis pathway in Affinity™ ECA5 between the two sampling times (made by Cytoscape, [60]). White circles represent metabolites. Grey circles represent genes that are not differentially regulated. Green circles represent down-regulated genes