Table 1 Production of bulk chemicals from CO2 in cyanobacteria at g/L scale
From: From cyanochemicals to cyanofactories: a review and perspective
Host | Chemical | Titer (g/L) | Strategies toward increased production |
|---|---|---|---|
7942 | Isobutyraldehyde [8] | 1.10 | Overexpression of rbcLS genes; Supplement of 50Â mM NaHCO3 |
6803 | d-Lactate [14] | 1.06 | Introducing a more efficient enzyme DldhL with a super-strong promoter; blocking poly-3-hydroxybutyrate and acetate pathways from acetyl-CoA node |
6803 | d-Lactate [15] | 1.14 | Introducing a more efficient enzyme GlyDH; expression of a soluble transhydrogenase |
7942 | 2,3-Butanediol [9] | 2.38 | Selection of key enzyme sADH with higher efficiency; using NADPH-dependent sADH; supplement of 50Â mM NaHCO3 |
7942 | Sucrose [15] | 3.50 | Expressing a symporter of protons and sucrose; minimizing glucose or sucrose consuming reactions |
6803 | Ethanol [4] | 5.50 | Selection of key enzymes with higher activity; blocking poly-3-hydroxybutyrate synthetic pathway |