Table 4 SSE between predicted (by iMAC868) and observed growth yields for acetate- and methanol-grown cells at different ratios of Na⁺ and H⁺ exchange by Mrp antiporter and varying ratios of Na⁺ and H⁺ uptake by ATP synthase

Methanol

3:1

2.11E−04

7.75E−06

2.21E−04

1.75E−02

2.53E−05

2:1

1.40E−07

8.58E−05

2.86E−04

1.67E−04

1.40E−07

1:1

4.57E−04

4.57E−04

4.57E−04

8.33E−05

8.33E−05

1:2

1.39E−03

6.73E−04

1.43E−04

1.43E−04

3.32E−05

1:3

1.57E−03

5.44E−04

1.26E−06

1.73E−04

1.78E−04

Acetate

3:1

7.97E−06

2.13E−04

Infeasible

3.93E−02

4.76E−05

2:1

8.00E−06

7.34E−05

2.96E−04

3.44E−04

8.00E−06

1:1

8.05E−06

8.05E−06

8.05E−06

5.51E−04

5.51E−04

1:2

8.09E−06

1.82E−04

7.45E−04

7.45E−04

2.10E−03

1:3

8.10E−06

3.45E−04

1.74E−03

8.36E−04

3.34E−03