Groups | LW/BW | SW/BW |
|---|
PBSa
| 0.050 ± 0.0082 | 0.0045 ± 0.0016 |
4.5 × 107CFUa
| 0.055 ± 0.0058 | 0.0047 ± 0.0013 |
4.5 × 109CFUa
| 0.046 ± 0.0079 | 0.0042 ± 0.0017 |
PBSb
| 0.054 ± 0.0057 | 0.0059 ± 0.0014 |
4.5 × 107CFUb
| 0.065 ± 0.0063 | 0.0052 ± 0.0018 |
4.5 × 109CFUb
| 0.045 ± 0.0061 | 0.0051 ± 0.0017 |
- The liver and body weight ratio (LW/BW), spleen and body weight ratio (SW/BW) were calculated in two separate studies, including the acute toxicity test (ATT, labeled as “a”) and bacterial dissemination test (BDT, labeled as “b”). There were three groups in both studies, PBS control, low dose (4.5 × 107 CFU) and high dose (4.5 × 109 CFU) treatment. The mice in ATT study were orally administrated for 3 days and observed for additional 7 days, whereas the mice in BDT assay were treated for 4 weeks
