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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Roles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis

Fig. 6

A comparison of FK506 (a) and FK520 (b) yields (mg/L) in engineered strains of S. tsukubaensis. Bars encompass 95 % of the sample population. Horizontal lines represent the median values, and perpendicular lines indicate extreme values (min, max). Asterisks represent statistically significant differences between different samples compared to control wild type samples (WT). WT: S. tsukubaensis NRRL 18488 (a); WT+: WT+ pSet152 (control strain with empty plasmid pSet152); ΔallR (f); ΔallR + allR (g); ΔallR + ccr1 (h); ΔallR + emc (i); ΔallR + allR_ecmOp (j); Δemc (b) Letters in brackets correspond to the labels of the plasmids constructs presented on Fig. 4)

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Microbial Cell Factories

ISSN: 1475-2859

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