Fig. 8
Dependency of the dispersed oxygen-sensitive nanoparticles concentration and the optical fiber orientation below the microtiter plate on the signal intensity. a Two different geometrical layouts below the MTP were tested with different orientation and optical fiber diameter. b The minimum signal intensity of 100 mV (dashed line) is required for a reliable DOT measurement. Measurement conditions: synthetic Wilms-MOPS medium without glucose, 48well Round Well Plate without optodes, VL = 800 µL, n = 1000 rpm, d0 = 3 mm, 23 °C