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Table 2 Binding kinetics

From: Enhanced production of a single domain antibody with an engineered stabilizing extra disulfide bond

Clone

ka (1/Ms)a

Average; SD

kd (1/S)a

Average; SD

KD (M)a

Average; SD

L1-G2

5.8 E+05; 6.4 E+04

6.3 E−04; 1.1 E−05

1.1 E−09; 1.7 E−10

L1-G2+

5.9 E+05; 1.1 E+05

1.3 E−03; 1.7 E−04

2.4 E−09; 6.6 E−10

L1-G2+neg

4.2 E+05; 3.9 E+04

1.4 E−03; 1.3 E−04

3.3 E−09; 2.0 E−10

L1-G2+neg2

5.4 E+05; 6.1 E+04

1.3 E−02; 3.5 E−04

2.3 E−08; 3.0 E−9

  1. aBased on four measurements
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Microbial Cell Factories

ISSN: 1475-2859

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