Table 1 Relative levels of production of germicidins and flaviolin in engineered strains
From: A Streptomyces coelicolor host for the heterologous expression of Type III polyketide synthase genes
Strain | Relative production (mAU × 103)/mg dry weight | |||
|---|---|---|---|---|
Germicidin A | Germicidin B7 | Total germicidins | Flaviolin | |
M1152/pIJ86 | 0.44 ± 0.02 | 0.42 ± 0.08 | 0.86 ± 0.10 | None |
M1317/pIJ12477 | None | None | None | None |
M1152/pIJ86 + sco7221 | 1.13 ± 0.14 | 5.58 ± 0.70 | 6.71 ± 0.84 | ND |
M1317/pIJ12477 + sco7221 | 1.88 ± 0.03 | 7.32 ± 0.27 | 9.19 ± 0.30 | ND |
M1152/pIJ12477 + sven5367 | ND | ND | ND | 1.72 ± 0.27 |
M1317/pIJ12477 + sven5367 | ND | ND | ND | 2.16 ± 0.05 |