Fig. 2
Physiological characteristics of the resveratrol producer FS09322 and of the congenic prototrophic strain CEN.PK113-7D. The data were obtained from aerobic glucose-limited chemostat cultures at various growth rates. a Culture viability measured by flow cytometry analysis of PI and CFDA staining (see "Methods" section). Open symbols indicate CEN.PK113-7D, closed symbols indicate FS09322. b Residual glucose concentration, closed symbols FS09322, empty circles CEN.PK113-7D. c Biomass-specific production rate of resveratrol (circles) coumaric acid (triangles) and phloretic acid (squares) in FS09322. d Biomass specific production rate of the pooled products (resveratrol + coumaric acid + phloretic acid + cinnamic acid) for FS09322. e Resveratrol and total product yield on glucose. f Biomass yield on glucose. g Biomass specific glucose uptake rate, FS09322 in closed symbols and CEN.PK113-7D in open symbols. h Distribution of the specific substrate uptake (qs) in FS09322 as calculated from the Herbert-Pirt equation (Eq. 2) for independent chemostats. In panels a–h, the shown data represent the average and standard deviation of at least two independent culture replicates for each dilution rate and each strain