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Table 2 Coded levels used for temperature, methanol constant feed flow-rate and DMSO in the CCD

From: An artificial neural network for membrane-bound catechol-O-methyltransferase biosynthesis with Pichia pastoris methanol-induced cultures

Input variables

Coded levels

−1

0

1

Temperature (°C)

20

25

30

Methanol constant feed rate (mL/h/L)

1

2

3

DMSO [% (v/v)]

4

5

6