Table 3 State variables initial values and simulation setup parameters
Symbol | Description | Unit | LBG H 1022a | CBS 8066b | CEN.PK113-7Dc | CEN.PK2-1Cd |
|---|---|---|---|---|---|---|
G 0 | Glucose initial value | g | 9 | 0 | 20 | 20 |
E 0 | Ethanol initial value | g | 0.1 | 0 | 0 | 0 |
P 0 | Glycolysis products initial value | g | 5 × 10−5 | 5 × 10−5 | 5 × 10−5 | 5 × 10−5 |
C M0 | Carbon metabolites initial value | g | 0.1 | 7 | 0.023 | 0.022 |
I 0 | Inhibitor initial value | g | 0 | 0 | 0 | 0 |
R 0 | Reserve compounds initial value | g | 0 | 0 | 0 | 0 |
D 0 | Dead cells initial value | g | 0 | 0 | 0 | 0 |
t 0 | Time of simulation start | h | 3 | 0 | 0 | 0 |
t F | Time of feeding start | h | – | 3.2 | 17 | 15 |
t END | Time of simulation end | h | 21 | 13 | 49 | 31; 40; 48 |
c F | Glucose concentration in feeding solution | g l−1 | – | 100 | 500 | 500 |
M F | Cell mass at beginning of feeding | g | – | 3.66 | 3.66 | 4.52; 4.14; 4.14 |
μ | Feeding rate | h−1 | – | 0.3 | 0.16 | 0.1; 0.16; 0.2 |
y R | Maximum biomass yield on glucose | – | – | 0.1 | 0.5 | 0.5 |