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Figure 4 | Microbial Cell Factories

Figure 4

From: Surface display of an anti-DEC-205 single chain Fv fragment in Lactobacillus plantarum increases internalization and plasmid transfer to dendritic cells in vitro and in vivo

Figure 4

Effect of surface expression of aDec on plasmid transfer to mouse DCs in vivo. Mice were orally administrated with Lp-WT/pValac-GFP, Lp-Lip-aDec/pValac-GFP, Lp-CWA-aDec/pValac-GFP or Lp-LysM-aDec/pValac-GFP during 4 days. At day 4 mice were sacrificed and DCs were extracted from the small intestine (a) or the colon (b). The percentage of DCs expressing GFP was measured by flow cytometry. Each point represents independent mice and the results are presented as mean ± SEM. Statistically significant differences are indicated as follows: *p < 0.05; **p < 0.01; ***p < 0.001.

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Microbial Cell Factories

ISSN: 1475-2859

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