Figure 11From: A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale Localization of amino acid exchanges of CYP11B1 that increase hydroxylation activity towards 11-deoxycortisol. L271M is located on the protein surface in the H-helix, while M286I resides in the I-helix. Helices are labeled with their eponymous letter. The structure represents the latest homology model [25] and figures were created with PyMOL Builds. Mutated amino acids and the heme are highlighted in black.Back to article page