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Figure 6 | Microbial Cell Factories

Figure 6

From: Synthetic signal sequences that enable efficient secretory protein production in the yeast Kluyveromyces marxianus

Figure 6

Substitution of the GLuc signal sequence with heterologous and homologous signal sequences. The GLuc signal sequence, up to the 16th E, was substituted with other signal sequences by connecting the C-terminal P of the other signal sequence to the site of the 16th E of GLuc. N-terminal K, R, N, and W are underlined and P and E are shown in bold letters. Signal sequences were utilized from hIL6: human interleukin 6; BlAmyL: Bacillus licheniformis alpha-amylase; hEPO: human erythropoietin; hLIF: human leukemia inhibitory factor; AoTAA: Aspergillus oryzae alpha-amylase; KmPGU1: Kluyveromyces marxianus polygalacturonase; hAZGP1: human zinc-binding alpha-2-glycoprotein; and SfGLU1: Saccharomycopsis fibuligera glucoamylase. Data were shown as in Figure 2.

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Microbial Cell Factories

ISSN: 1475-2859

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