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Figure 4 | Microbial Cell Factories

Figure 4

From: Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems

Figure 4

Characterization of 4KB-PE40 IT immunospecificity for CD22 expressed on Daudi cells. The cytotoxic assay was performed incubating Daudi cells for 72 hours with increasing concentrations of 4KB-PE40 in the presence (pink squares) or absence (blue diamonds) of a fixed concentration of the corresponding parental 4KB128 monoclonal antibody. Inhibition of protein synthesis is expressed as percentage of [14C]-leucine incorporation compared to the control samples (untreated cells).

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