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Table 1 Astaxanthin production by combined overexpression of mevalonate synthetic pathway genes in X. dendrorhous

From: Development of a multi-gene expression system in Xanthophyllomyces dendrorhous

Overexpressing Gene(s)

Cell concentration [OD600]

Astaxanthin content [mg/g-cell]

Astaxanthin concentration [mg/L]

vector control

16.2 ± 0.34 (1.0)

0.26 ± 0.009 (1.0)

1.6 ± 0.09 (1.0)

hmgR

16.5 ± 0.04 (1.0)

0.36 ± 0.005 (1.4)

2.2 ± 0.03 (1.4)

acaT/hmgS/hmgR

17.0 ± 0.16 (1.0)

0.39 ± 0.006 (1.5)

2.5 ± 0.06 (1.6)

  1. Samples were taken after culture for 72 h.
  2. The culture conditions are described in “Methods”.
  3. Parentheses represent the relative values.
  4. The values are represented as mean ± SD (n ≥ 3).