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Figure 1 | Microbial Cell Factories

Figure 1

From: Deletion of the gene encoding the reductase component of 3-ketosteroid 9α-hydroxylase in Rhodococcus equi USA-18 disrupts sterol catabolism, leading to the accumulation of 3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid and 1,4-androstadiene-3,17-dione

Figure 1

The simplified illustration of the cholesterol catabolic pathway in Rhodococcus sp. CHO, 3HSDH, CYP125, KSTD and KSH denote cholesterol oxidase, 3-hydroxysteroid dehydrogenase, cytochrome P450 125, 3-ketosteroid Δ 1 dehydrogenase and 3-ketosteroid 9α-hydroxylase, respectively. The arrow with dashed line denotes multiple enzymatic steps.

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