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Figure 2 | Microbial Cell Factories

Figure 2

From: The use of fosmid metagenomic libraries in preliminary screening for various biological activities

Figure 2

Effects of extracts from library clones on viability of human cells. Viability of wild-type HDFa (triangles) and cancer MCF-7 (squares) cells was assessed in media supplemented with various amounts of the extract from bacteria bearing the 123–3 clone. Mean values from 3 independent experiments are shown with error bars indicating SD. Statistically significant differences (p < 0.05 in the t-test) between two cell lines are indicated by asterisks. Viability of MCF-7 cells in the presence of the extract was significantly (p < 0.05) decreased relative to cultures without the extract at the same concentrations, thus no additional symbols are shown. The presence of the extract did not cause any significant decrease in viability of HDFa cells at all tested concentrations (p > 0.05).

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