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Figure 6 | Microbial Cell Factories

Figure 6

From: The important ergot alkaloid intermediate chanoclavine-I produced in the yeast Saccharomyces cerevisiae by the combined action of EasC and EasE from Aspergillus japonicus

Figure 6

Effects of host engineering on chanoclavine-I production. Concentration (mg/l) of chanoclavine-I, was measured in the growth medium, of a chanoclavine-I producing control strain (A) and after over-expression of Pdi1 (B), Ero1(C), or Fad1 (D). Over-expression of these native yeast genes all resulted in an increased production of chanoclavine-I, relative to the control. All strains expressed the integrated, heterologous pathway to chanoclavine-I.

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Microbial Cell Factories

ISSN: 1475-2859

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