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Figure 1 | Microbial Cell Factories

Figure 1

From: The important ergot alkaloid intermediate chanoclavine-I produced in the yeast Saccharomyces cerevisiae by the combined action of EasC and EasE from Aspergillus japonicus

Figure 1

Biosynthetic pathway to chanoclavine-I and chanoclavine aldehyde. Ergot alkaloids are synthesized from tryptophan and dimethylallylpyrophosphate (DMAPP, not shown), via dimethylallyltryptophan (DMAT), N-methyl-4-dimethylallyltryptophan (Me-DMAT), chanoclavine-I, and chanoclavine aldehyde. The aldehyde is considered to be the branch point in the biosynthetic pathways of different ergot alkaloids, typically via intermediates like agroclavine and festuclavine.

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Microbial Cell Factories

ISSN: 1475-2859

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