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Figure 3 | Microbial Cell Factories

Figure 3

From: Physiological characteristics of the extreme thermophile Caldicellulosiruptor saccharolyticus: an efficient hydrogen cell factory

Figure 3

Schematic representation of the suggested circulation of energy carriers in catabolism and anabolism in C. saccharolyticus during exponential growth (A), and non-growth (B), and its influence on metabolite formation. During exponential growth, there is a high energy demand in the cells. The formation of acetate allows maximum ATP gain and high levels of PPi secure economical use of ATP, including the inhibition of LDH activity and prevention of lactate formation. During non-growth, the ATP demands in the cells are reduced and LDH activity is restored due to the absence of PPi.

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