Table 1 Summary statistics of metabolic reconstruction for two yeast models
Genome characteristics | P. pastoris | S. cerevisiae | ||
|---|---|---|---|---|
Genome length | 9.3 Mbp | 12.1 Mbp | ||
G+C content | 41.1% | 38.3% | ||
Coding genes | 5,313 | 6,607 | ||
Model characteristics | Â | Â | Â | Â |
No. of genes | 668 | 904 | ||
No. of gene-associated reactions | 1,007 | 1,043 | ||
No. of other reactions | 354 | 534 | ||
No. of internal reactions | 1,212 | 1,413 | ||
No. of exchange reactions | 149 | 164 | ||
No. of metabolites | 1,177 | 1,228 | ||
Compartment | No. of metabolites | No. of reactions | No. of metabolites | No. of reactions |
Cytosol | 607 | 623 | 634 | 709 |
Endoplasmic reticulum | 28 | 15 | 28 | 15 |
Extracellular matrix | 149 | 12 | 164 | 14 |
Golgi apparatus | 15 | 4 | 17 | 6 |
Mitochondria | 235 | 163 | 241 | 175 |
Nucleus | 35 | 16 | 40 | 16 |
Peroxisome | 84 | 66 | 80 | 65 |
Vacuole | 24 | 3 | 24 | 3 |
Inter-compartment | - | 452 | - | 574 |
Total | 1,177 | 1,361 | 1,228 | 1,577 |