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Figure 1 | Microbial Cell Factories

Figure 1

From: Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters

Figure 1

Representation of the pL/pR promoters controlled by the cI857 repressor. The cI857 interacts with three operator domains (oL3/oR3, oL2/oR2, and oL1/oR1), repressing transcription. The heterologous gene is localized downstream from the pL or pR promoters. a) The cI857 forms dimers that bind to the oL or oR region and block transcription by RNA polymerase. b) The interaction of cI857 with oL or oR regions, is released up to 37°C, permitting transcription by RNA polymerase.

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Microbial Cell Factories

ISSN: 1475-2859

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