Figure 2

Metabolic flux profiles of C. glutamicum in the exponential growth phase. (a) The metabolic fluxes obtained by performing ¹³C-tracer experiment [10] and (b) the simulated metabolic fluxes with the same GUR and OUR are presented. The black and gray arrows represent reactions with non-zero and zero fluxes, respectively. Abbreviations are as follows: E4P, erythrose-4-phosphate; 6PG, 6-phospho-d-gluconate; Xu5P, xylulose-5-phosphate; Pyr, pyruvate; F6P, fructose-6-phosphate; GAP, glyceraldehyde-3-phosphate; R5P, ribose-5-phosphate; Ru5P, ribulose-5-phosphate; S7P, sedoheptulose-7-phosphate; G6P, glucose-6-phosphate; LYS, lysine; Suc, succinate; Cit, citrate; IsoCit, Isocitrate; aKG, a-ketoglutarate; MAL, malate; FUM, fumarate; OAA, oxaloacetate.