Figure 1
From: Factors affecting plasmid production in Escherichia coli from a resource allocation standpoint
Metabolic reaction network of plasmid production in E. coli for aerobic growth on glucose minimal medium. Points of carbon entry are boxed. Points of carbon exit are circled except for drains on precursor metabolites for biomass synthesis, which are denoted in blue and by large shaded arrowheads. Double-ended arrows represent potentially reversible reactions, with the larger arrowhead depicting the net direction. Key fluxes discussed in the text are labeled as r i . Specific details on reaction stoichiometries can be found in the Methods, and abbreviations are defined in the Abbreviations section.