Figure 4
From: Metabolic responses to pyruvate kinase deletion in lysine producing Corynebacterium glutamicum
In vivo carbon flux distribution in the central metabolism of lysine producing C. glutamicum lysCfbr (top) and its pyruvate kinase deficient derivative C. glutamicum lysCfbr Δpyk (bottom) during growth on glucose. All fluxes are given as a molar percentage of the mean specific glucose uptake rate of qGlc = 4.6 mmol g-1 h-1 (for lysCfbr) and 4.5 mmol g-1h-1 (for lysCfbr Δpyk), which is set to 100 %. The errors reflect the corresponding 90 % confidence intervals for the different fluxes, obtained by Monte-Carlo analysis. For reversible metabolic reactions, the flux reversibility, i.e. the ratio of exchange flux to net flux, is additionally given in brackets and the direction of the net flux is indicated by an arrow.