Table 1 The top three gene ontology (GO) classes in each of the eight clusters in Figure 1. n is the number of the genes with the specified function, % is the percentage of the genes in the cluster with the specified function, and p-value is the binomial distribution probability [33]. (Total number of genes in clusters 1 to 8: 484, 514, 127, 182, 22, 22, 34 and 54, respectively)

GO:0009058

Biosynthesis

159

32.9

1.96E-23

GO:0044249

Cellular biosynthesis

148

30.6

1.95E-21

GO:0044238

Primary metabolism

286

59.1

5.51E-19

GO:0006091

Generation of precursor metabolites and energy

67

13.0

5.89E-25

GO:0015980

Energy derivation by oxidation of organic compounds

57

11.1

6.24E-21

GO:0006119

Oxidative phosphorylation

20

3.9

5.25E-11

GO:0006896

Golgi to vacuole transport

5

3.9

1.39E-05

GO:0006892

Post-Golgi transport

6

4.7

2.10E-04

GO:0042147

Retrograde transport, endosome to Golgi

3

2.4

6.40E-04

GO:0044242

Cellular lipid catabolism

2

1.1

4.99E-03

GO:0016042

Lipid catabolism

2

1.1

4.99E-03

GO:0006000

Fructose metabolism

2

1.1

4.99E-03

GO:0006790

Sulphur metabolism

6

27.3

8.16E-09

GO:0000096

Sulphur amino acid metabolism

4

18.2

1.71E-06

GO:0015837

Amine transport

4

18.2

8.44E-06

GO:0000017

Alpha-glucoside transport

2

9.1

1.00E-04

GO:0042946

Glucoside transport

2

9.1

1.00E-04

GO:0008643

Carbohydrate transport

2

9.1

4.21E-03

GO:0009082

Branched chain family amino acid biosynthesis

5

14.7

2.50E-09

GO:0009081

Branched chain family amino acid metabolism

5

14.7

7.00E-09

GO:0009098

Leucine biosynthesis

3

8.8

1.30E-06

GO:0000002

Mitochondrial genome maintenance

4

7.4

3.24E-05

GO:0051294

Establishment of spindle orientation

2

3.7

1.66E-03

GO:0051293

Establishment of spindle localization

2

3.7

1.66E-03