Figure 2From: Folding and assembly of large macromolecular complexes monitored by hydrogen-deuterium exchange and mass spectrometryMechanism of HDX. (A) Mechanism of the chemical step. Inset on the right illustrates the pH and temperature (solid line 25°C, dashed line 0°C) dependence of the intrinsic exchange rate (B) Influence of quaternary, tertiary and secondary structure on HDX. (C) Overall reaction scheme and the two limiting cases.Back to article page