Figure 11From: Hitting bacteria at the heart of the central dogma: sequence-specific inhibitionSchematic representation of bis-PNA binding. (Top) Bis-PNA (depicted in red) can bind to both DNA and RNA through Hoogsteen base pairing (unbroken line) and Watson-Crick base pairing (dotted line). (Bottom) An example on Hoogsteen (on the left) and Watson-Crick (on the right) base pairing is shown in detail.Back to article page