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Figure 3 | Microbial Cell Factories

Figure 3

From: Differential gene expression in recombinant Pichia pastoris analysed by heterologous DNA microarray hybridisation

Figure 3

Schematic representation of the observed regulations in the sulfur, methionine and S-adenosyl-methionine metabolism. Gene names are framed. APS: adenylylsulfate, PAPS: 3'-phosphoadenylyl-sulfate, MET3: ATP sulfurylase, MET6: N5-methyltetrahydrofolate homocysteine methyltransferase, MET10: sulfite reductase, MET14: adenylylsulfat kinase, MET16: 3'-phosphoadenylyl-sulfate reductase, MET17: O-acetylhomoserine (thiol)-lyase, SAH1: S-adenosyl-L-homocysteine hydrolase, SAM1: S-adenosylmethionine synthetase, SAM2: S-adenosylmethionine synthetase. (â–²) upregulation upon shift from glycerol to methanol; (â–¼) downregulation upon shift from glycerol to methanol; (ns) no significant values obtained.

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