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Figure 1 | Microbial Cell Factories

Figure 1

From: Strategies for the recovery of active proteins through refolding of bacterial inclusion body proteins

Figure 1

Simplified model of correct folding versus misfolding and aggregation. The correct protein folding pathway (1) often competes with misfolding (2) and aggregation (3). Aggregation occurs among intermediates with exposed hydrophobic patches, which are buried in the correctly folded protein (blue lines, hydrophilic solvent-exposed parts of the protein; red lines: hydrophobic patches).

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Microbial Cell Factories

ISSN: 1475-2859

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