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Table 3 Knockout candidate genes for enhancing 3HP production obtained by gene knockout simulation

From: Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli

Knockout genes

3HP yield (C-mol%)

Specific growth rate relative to wild-type

iAF1260-3HP

0

100%

ΔtpiA Δzwf

70.5

48%

ΔtpiA Δpgi

70.5

48%

ΔtpiA Δedd

70.5

48%

ΔtpiA ΔgldA

69.0

47%

ΔtpiA ΔfsaB

69.0

47%