Figure 2
Metabolic flux distributions based on the genome-scale metabolic model. Metabolic flux distribution for the iAF1260-3HP (A), Δzwf (B), ΔtpiA (C), and ΔtpiA Δzwf (D) models are shown. Flux values are normalized by the glycerol uptake rate to 100%. Width of the black arrow corresponds to the relative flux value of glycerol uptake rate. Gray arrow indicates the flux of the corresponding reaction was 0. Abbreviations: 3HP, 3-hydroxypropionic acid; 3HPA, 3-hydroxypropionaldehyde; 1,3-PDO, 1,3-propanediol; DHA, dihydroxyacetone; DHAP, dihydroxyacetone phosphate; G3P, glycerol 3-phosphate; G6P, glucose 6-phosphate; 6PG, 6-phospho-gluconate; 6PGL, 6-phospho-glucono-1,5-lactone; F6P, fructose 6-phosphate; FBP, fructose 1,6-bisphosphate; Ru5P, ribulose 5-phosphate; R5P, ribose 5-phosphate; S7P, sedoheptulose 7-phosphate; GAP, glyceraldehyde 3-phosphate; X5P, xylulose 5-phosphate; E4P, erythrose4-phosphate; MGO, methylglyoxal; PEP, phosphoenolpyruvate; Pyr, pyruvate; AcCoA, acetyl-CoA; AcetP, acetyl phosphate; EtOH, ethanol; Oxa, oxaloacetate; Cit, citrate; IsoCit, isocitrate; α-KG, α-ketoglutarate; Suc, succinate; Fum, fumarate; Mal, malate; Glyox, glyoxylate; Q, ubiquinone; QH2, ubiquinol.