Figure 1From: Double mutation of cell wall proteins CspB and PBP1a increases secretion of the antibody Fab fragment from Corynebacterium glutamicum Schematic diagram of the co-expression cassette of Fab(H+L) in pPKStrastFabHL. The Fab(H+L) expression plasmid pPKStrastFabHL was constructed as described in Methods. The HC and LC genes of the anti-HER2 Fab fragment (shaded bars) fused with the signal peptide of CspA from C. ammoniagenes (open bars) were expressed under control of the cspB promoter from C. glutamicum (thick arrows).Back to article page