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Figure 1 | Microbial Cell Factories

Figure 1

From: Metabolic engineering of Pseudomonas sp. strain VLB120 as platform biocatalyst for the production of isobutyric acid and other secondary metabolites

Figure 1

Pathways for isobutyric acid synthesis and its degradation in Ps . sp. strain VLB120. OM: outer membrane, IM: inner membrane, ADH: alcohol dehydrogenase, ALDH: aldehyde dehydrogenase, alsS: acetolactate synthase, bkd: branched-chain alpha-keto acid dehydrogenase gene cluster, gcd: glucose dehydrogenase, ilvC: ketol-acid reductoisomerase, ilvD: dihydroxy acid dehydratase, ilvE: branched-chain-amino-acid transaminase, kivd: 2-keto acid decarboxylase, leuA: 2-isopropylmalate synthase, leuB: 3-isopropylmalate dehydrogenase, leuC: isopropylmalate isomerase, mmsA: methylmalonate-semialdehyde dehydrogenase, mmsB: 3–hydroxyisobutyrate dehydrogenase, pyc: pyruvate carboxylase, panB: ketopantoate hydroxymethyl transferase, panE: ketopantoic acid reductase, panC pantothenate synthetase [19, 40, 53].

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Microbial Cell Factories

ISSN: 1475-2859

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